Charlie Murphy, Eddie's older brother, and a very successful and popular stand-up comedian in his own right has died ... TMZ has learned.
According to Charlie's manager, he died from leukemia Wednesday morning in a NYC hospital. He'd been going undergoing chemotherapy. Family members say they're absolutely shocked because they thought he was getting better.
Charlie famously co-starred on "Chappelle's Show" in some of Dave's most memorable skits ... including the nights Charlie partied with Rick James and Prince.
Charlie also co-wrote some of Eddie Murphy's movies, like "Norbit" and "Vampire in Brooklyn." He co-starred in "Are We There Yet?," "The Boondocks" and "Black Jesus."
Charlie's wife, Tisha Taylor Murphy, died in 2009 from cervical cancer. They had 2 children, and he had another from a previous relationship.
Charlie was 57.